Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Myasthenia Gravis: Overview and Treatment

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Parkinson's Disease: Treatment

Parkinson's Disease: Treatment

Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...

Prosopagnosia

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Big Data and Trustworthy AI for Heart Failure: A Review.

Circulation. Heart failure·2026

Same author

Subtyping Alzheimer's disease and Parkinson's disease using longitudinal electronic health records.

Nature aging·2026

Same author

A transformer-based survival model for prediction of all-cause mortality in patients with heart failure: a multi-cohort study.

NPJ digital medicine·2026

Same author

Redefining endpoints in heart failure clinical trials: the emerging role of wearable technologies in contemporary trial design.

Heart failure reviews·2025

Same author

Unique place of ambulatory EEG (aEEG) in management of epilepsy.

Epilepsy & behavior : E&B·2025

Same author

Refined selection of individuals for preventive cardiovascular disease treatment with a transformer-based risk model.

The Lancet. Digital health·2025

Search research articles

Related Experiment Video

Updated: Feb 24, 2026

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

Vertical gaze palsy due to medication error.

Shishir Rao^1,2, Meghan Harper-Shankie^1,2,3, Rajkumar Agarwal^1,2,3

¹Division of Neurology, Children's Hospital of Michigan, Detroit, MI, USA 48201.

Epilepsy & Behavior Case Reports

|August 11, 2017

Summary

This summary is machine-generated.

A teenage boy experienced seizures due to an antiseizure medication mix-up. Drug toxicity led to vertical gaze palsy, but recovery was complete after stopping the medication.

Keywords:

Gaze palsy Lamotrigine Medication error Oxcarbazepine

More Related Videos

Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm

Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm

Published on: April 28, 2020

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

Related Experiment Videos

Last Updated: Feb 24, 2026

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm

Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm

Published on: April 28, 2020

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

Area of Science:

Neurology
Clinical Toxicology

Background:

Seizures are a common neurological disorder in adolescents.
Accurate medication management is crucial for effective treatment and patient safety.

Observation:

A teenage patient presented with new-onset seizures.
The patient received an incorrect, high dose of an antiseizure medication due to a drug mix-up.
This overdose resulted in the unusual symptom of vertical gaze palsy.

Findings:

Drug toxicity from antiseizure medication overdose can manifest as vertical gaze palsy.
Prompt identification of medication errors is vital for patient outcomes.
Discontinuation of the offending agent led to full clinical recovery.

Implications:

Highlights the importance of meticulous drug handling and verification processes in clinical settings.
Underscores the need for clinicians to recognize rare side effects of medication overdose.
Emphasizes the potential for complete recovery from drug-induced neurological deficits with timely intervention.