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DISCONTOOLS: Identifying gaps in controlling bovine spongiform encephalopathy.
M Simmons1, G Ru2, C Casalone3
1OIE, National and EU Reference Laboratory for BSE and Scrapie, Department of Pathology, APHA Weybridge, Addlestone, Surrey, UK.
Transboundary and Emerging Diseases
|August 11, 2017
Summary
Bovine spongiform encephalopathy (BSE) cases decline with feed bans, but uncertainties in pathogenesis and epidemiology remain. Atypical BSE strains pose zoonotic risks, necessitating continued surveillance and feed controls to prevent future epidemics.
Area of Science:
- Veterinary Medicine
- Epidemiology
- Food Safety
Background:
- Bovine spongiform encephalopathy (BSE) remains a concern despite declining cases.
- Uncertainties persist regarding BSE pathogenesis, immunology, and epidemiology.
- Atypical BSE strains (L-BSE, H-BSE) exhibit different characteristics and zoonotic potential.
Purpose of the Study:
- To summarize the 2016 DISCONTOOLS project gap analysis on BSE.
- To identify remaining uncertainties and challenges in BSE control.
- To assess the implications of relaxing control measures.
Main Methods:
- Literature review
- Expert knowledge synthesis
- Analysis of BSE control strategies
Main Results:
- BSE cases continue to decline with strict feed bans.
- Atypical BSE strains present distinct pathologies and zoonotic potential.
- Current diagnostic methods are limited to post-mortem testing.
Conclusions:
- Continued vigilance and surveillance are crucial, even with declining cases.
- Relaxing feed controls or surveillance may increase risks.
- Preventing intraspecies and interspecies recycling of BSE agents is vital.

