[Management of chronic osteomyelitis by long-term antibiotic suppression]

C Kabore1, A Wouters2, F Frippiat3

  • 1Université de Liège, Belgique.

Revue Medicale De Liege
|August 11, 2017
PubMed

Insights

Long-term suppressive antibiotic therapy offers a viable alternative for chronic osteomyelitis in non-surgical candidates. This approach requires careful consideration of potential risks, costs, and patient quality of life.

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Pharmacology

Background:

  • Chronic osteomyelitis is a persistent bone infection affecting various bone structures and surrounding tissues.
  • It presents a significant therapeutic challenge due to its prolonged nature and complex management involving surgery and antibiotics.

Observation:

  • A case of chronic osteomyelitis was managed using long-term suppressive antibiotic therapy.
  • This treatment was considered for a patient with inoperable clinical circumstances.

Findings:

  • Long-term suppressive antibiotic therapy can be a reasonable alternative to surgical intervention for chronic osteomyelitis.
  • This management strategy necessitates a thorough evaluation of associated risks, including side effects and antimicrobial resistance.

Implications:

  • The use of suppressive antibiotics for chronic osteomyelitis requires balancing benefits against risks like resistance and side effects.
  • Cost-effectiveness and impact on patient quality of life are crucial factors in this therapeutic decision.

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