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Compact Quantum Dots for Single-molecule Imaging
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Immunoglobulin binding (B1) domain mediated antibody conjugation to quantum dots for in vitro and in vivo molecular

Setsuko Tsuboi1, Akira Sasaki, Takao Sakata

  • 1Laboratory for Nano-Bio Probes, Quantitative Biology Center (QBiC), RIKEN, Suita, Osaka 565-0874, Japan. tjin@riken.jp.

Chemical Communications (Cambridge, England)
|August 11, 2017
PubMed

A facile method for the preparation of antibody-quantum dot (QD) conjugates using the immunoglobulin binding (B1) domain of protein G is presented. The utility of antibody-QD conjugates using the B1 domain is demonstrated for fluorescence imaging of breast tumor cells in vitro and in vivo.

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