Related Experiment Video
Updated: Feb 24, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
Published on: June 3, 2016
Epigenetic Regulation of Adipokines
Tho X Pham1, Ji-Young Lee2,3
1Department of Nutritional Sciences, University of Connecticut, 216 Advanced Technology Laboratory Building, 1392 Storrs Road, Storrs, CT 06269, USA. Tho.Pham@uconn.edu.
Abstract:
Adipose tissue expansion in obesity leads to changes in the expression of adipokines, adipocyte-specific hormones that can regulate whole body energy metabolism. Epigenetic regulation of gene expression is a mechanism by which cells can alter gene expression through the modifications of DNA and histones. Epigenetic mechanisms, such as DNA methylation and histone modifications, are intimately tied to energy metabolism due to their dependence on metabolic intermediates such as S-adenosylmethionine and acetyl-CoA. Altered expression of adipokines in obesity may be due to epigenetic changes. The goal of this review is to highlight current knowledge of epigenetic regulation of adipokines.
More Related Videos
09:20An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function
Published on: May 4, 2021
10:40Characterization of Adipocyte-Derived Extracellular Vesicle Secretion Using a CD63-GFP Reporter Mouse Model In Vivo and In Vitro
Published on: December 5, 2025
Related Concept Videos
Epigenetic Regulation
Epigenetic Regulation
X-chromosome...
Regulation of Food Intake
Regulation of Metabolism
Cell Specific Gene Expression
Master Transcription Regulators