Bilateral internal thoracic arteries: what is the State of the ART?

Bobby Yanagawa1, Subodh Verma, John D Puskas

  • 1aDivision of Cardiac Surgery, St Michael's Hospital, Toronto, Ontario, CanadabDepartment of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.

Insights

Bilateral internal thoracic artery (BITA) grafting offers protective benefits in coronary artery bypass grafting, despite potential sternal complications. Wider adoption is recommended, pending long-term trial results.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Surgical Innovation

Background:

  • Coronary artery bypass grafting (CABG) is a cornerstone treatment for coronary artery disease.
  • The use of bilateral internal thoracic artery (BITA) grafts in CABG has been debated due to potential benefits and risks.
  • Evidence synthesis is crucial for optimizing surgical strategies in CABG.

Purpose of the Study:

  • To review the current evidence on the use of BITA in CABG.
  • To evaluate the efficacy, safety, and outcomes associated with BITA grafting.
  • To inform clinical practice and future research directions in arterial revascularization.

Main Methods:

  • Comprehensive literature review of observational studies and clinical trials.
  • Analysis of graft patency, clinical outcomes, and complications associated with BITA use.
  • Examination of data from the Arterial Revascularization Trial (ART).

Main Results:

  • Observational data predominantly support BITA use, showing protective effects on graft patency and clinical outcomes.
  • No significant difference in outcomes based on the specific configuration of BITA grafting.
  • Increased risk of sternal complications is a concern, but can be mitigated with sternal-sparing techniques.
  • Interim ART results at 5 years did not demonstrate a clinical benefit for BITA over single internal thoracic artery, with final results pending.

Conclusions:

  • Current literature supports the use of BITA for surgical revascularization in CABG.
  • Anticipation of long-term results from the Arterial Revascularization Trial is high.
  • A consensus suggests increasing the proportion of CABG procedures utilizing BITA grafts.
Abstract

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