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Updated: Feb 24, 2026

Evaluation of Amino Acid Consumption in Cultured Bone Cells and Isolated Bone Shafts
Published on: April 13, 2022
Stability and assessment of amino acids in parenteral nutrition solutions
Nina Unger1, Ulrike Holzgrabe1
1Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.
Abstract:
Sterile amino acid solutions are applied in medical care as part of Total Parenteral Nutrition systems. Typical formulations consist of variable admixtures of essential and non-essential amino acids together with carbohydrates, electrolytes, vitamins, trace element solutions and lipid emulsions. The complexity of these formulations gives rise to stability and compatibility reflections. This review focuses on amino acid stability in pure amino acid solution and name methods of assessment. Incompatibilities of amino acids with the other ingredients are matter of concern in clinical practice and evaluated for relevance.
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