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Updated: Feb 24, 2026

Nanopore DNA Sequencing for Metagenomic Soil Analysis
Published on: December 14, 2017
Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria
Terence S Crofts1, Bin Wang2,3, Aaron Spivak4
1Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, Missouri, USA tcrofts@path.wustl.edu.
Abstract:
Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic.
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