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Draft Genome Sequence of Mycobacterium avium 11
Michelle Yee1, David Klinzing2, Jun-Rong Wei3,4
1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Genome Announcements
|August 12, 2017
Summary
Mycobacterium avium causes most nontuberculous mycobacteria lung disease. Researchers sequenced the M. avium 11 genome to aid in discovering new drugs for this infection.
Area of Science:
- Microbiology
- Genomics
Background:
- Nontuberculous mycobacteria (NTM) lung disease is primarily caused by Mycobacterium avium.
- Current chemotherapy options for NTM infections are limited, necessitating novel drug development.
Purpose of the Study:
- To report the draft genome sequence of Mycobacterium avium 11.
- To provide a resource for NTM-focused drug discovery.
Main Methods:
- Whole-genome sequencing of Mycobacterium avium 11.
Main Results:
- The draft genome sequence of Mycobacterium avium 11 has been generated.
- This sequence provides a genetic blueprint for M. avium.
Conclusions:
- The genome sequence of M. avium 11 is a valuable tool for identifying new drug targets.
- This resource will facilitate the development of novel therapeutics against Mycobacterium avium infections.
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