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Related Experiment Video

Updated: Feb 24, 2026

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

Published on: April 1, 2016

Paper-based microfluidic devices by asymmetric calendaring.

S Oyola-Reynoso¹, C Frankiewicz¹, B Chang¹

¹Department of Materials Science and Engineering, Iowa State University, 528 Bissel Rd, Ames, Iowa 50011, USA.

Biomicrofluidics

|August 12, 2017

Summary

This summary is machine-generated.

We developed Targeted Asymmetric Calendaring and Hydrophobization (TACH), a simple, affordable method to create paper-based microfluidic channels. This technique efficiently produces hydrophobic channels with tunable flow properties for various applications.

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Last Updated: Feb 24, 2026

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

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Area of Science:

Materials Science
Microfluidics
Analytical Chemistry

Background:

Paper-based microfluidic devices offer low-cost diagnostics.
Creating robust, reliable microchannels on paper remains a challenge.
Existing methods often involve multiple steps or specialized equipment.

Purpose of the Study:

To introduce a novel, one-step method for fabricating paper-based microfluidic channels.
To demonstrate the efficiency and affordability of the TACH method.
To characterize the physical and flow properties of the fabricated channels.

Main Methods:

Selective calendaring and hydrophobization of paper using a rolling ball and a carrier solvent.
Asymmetric mechanical modification under controlled stress (σz).
Tomography for channel dimension analysis and wicking for hydrophobic barrier assessment.

Main Results:

Successfully fabricated open-channel paper-based microfluidics using the TACH method.
Achieved variable channel widths (10s-100s of microns) and depths.
Demonstrated effective hydrophobic barriers preventing leakage and tunable flow properties.

Conclusions:

TACH is a simple, efficient, and affordable technique for producing paper microfluidic channels.
The method allows for precise control over channel dimensions and hydrophobic properties.
The resulting channels exhibit flow characteristics comparable to conventional microfluidic devices.