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Updated: Feb 24, 2026

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
Published on: November 17, 2011
Ionic Liquid-Liquid Chromatography: A New General Purpose Separation Methodology
Leslie Brown1, Martyn J Earle2, Manuela A Gîlea3
1AECS-QuikPrep Ltd, 55 Gower Street, London, WC1 6HQ, UK.
Abstract:
Ionic liquids can form biphasic solvent systems with many organic solvents and water, and these solvent systems can be used in liquid-liquid separations and countercurrent chromatography. The wide range of ionic liquids that can by synthesised, with specifically tailored properties, represents a new philosophy for the separation of organic, inorganic and bio-based materials. A customised countercurrent chromatograph has been designed and constructed specifically to allow the more viscous character of ionic liquid-based solvent systems to be used in a wide variety of separations (including transition metal salts, arenes, alkenes, alkanes, bio-oils and sugars).
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