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Extubation in patients undergoing extracorporeal life support
Amélie Bataillard1, Amélie Hebrard1, Lucie Gaide-Chevronnay1
1Division of Anesthesiology and Critical Care, Department of Cardiac Surgery, University Hospital of Grenoble, Grenoble - France.
The International Journal of Artificial Organs
|August 12, 2017
Summary
Stopping sedation and extubating patients on extracorporeal life support (ECLS) is feasible. This strategy may improve survival rates for critically ill patients requiring cardiopulmonary support.
Area of Science:
- Critical Care Medicine
- Cardiopulmonary Support
- Mechanical Ventilation
Background:
- Extracorporeal life support (ECLS) treats severe cardiac/respiratory failure.
- High mortality is linked to patient condition severity.
- ECLS typically involves heavy sedation.
Purpose of the Study:
- To assess the feasibility of discontinuing sedation.
- To enable extubation for patients on ECLS.
- To evaluate the impact of extubation on outcomes.
Main Methods:
- 196 patients on ECLS over 4 years were analyzed.
- Sedation was stopped to facilitate extubation.
- Extubated patients were compared to non-extubated patients.
Main Results:
- Extubated patients showed reduced ventilator-associated pneumonia.
- Lack of extubation, ECLS duration, and age were independent risk factors for mortality.
- Stopping sedation and extubation were feasible in selected ECLS patients.
Conclusions:
- Discontinuing sedation and extubating ECLS patients is achievable.
- This approach may serve as a survival factor.
- Further research into patient selection is warranted.
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