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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-IV: Nursing Management01:30

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Asthma-III: Symptoms and Complications01:24

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Developing core economic outcome sets for asthma studies: a protocol for a systematic review.

Natalia Hounsome1, Deborah Fitzsimmons2, Ceri Phillips2

  • 1Asthma UK Centre for Applied Research, Centre ofPrimary Care and Public Health, Queen Mary Universityof London, London, UK.

BMJ Open
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Summary

This study develops core outcome sets for asthma economic evaluations by systematically reviewing literature and interviewing stakeholders. The goal is to standardize reporting of economic outcomes in asthma research.

Keywords:
asthma trialscore outcome seteconomic evaluation

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Area of Science:

  • Health Economics
  • Respiratory Medicine
  • Research Methodology

Background:

  • Core outcome sets standardize outcome reporting in clinical studies.
  • Economic evaluations in asthma research lack standardized outcome measures.
  • This study addresses the need for core outcome sets in asthma economic evaluations.

Purpose of the Study:

  • To develop core outcome sets for economic evaluations in asthma.
  • To identify and refine a comprehensive list of economic outcomes for asthma studies.

Main Methods:

  • Conducting a systematic literature review of studies published from 1990-2017 reporting economic outcomes in asthma.
  • Performing a realist synthesis review to analyze identified economic outcomes.
  • Conducting semistructured interviews with diverse stakeholders to identify additional relevant outcomes.
  • Utilizing a Delphi survey to refine outcomes into a core outcome set.

Main Results:

  • A preliminary list of economic outcomes will be generated from the systematic review.
  • Stakeholder interviews will identify outcomes not previously reported.
  • The Delphi survey will lead to a consensus-based core outcome set.

Conclusions:

  • The developed core outcome sets will standardize economic outcome reporting in asthma research.
  • This standardization will improve the comparability and quality of economic evaluations in asthma.
  • Findings will be disseminated to stakeholders to inform guideline development and research funding.