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Acyl modification and binding of mitochondrial ACP to multiprotein complexes

Heike Angerer1, Stefan Schönborn2, Jan Gorka2

  • 1Goethe University Frankfurt, Medical School, Institute of Biochemistry II, Structural Bioenergetics Group, Max-von-Laue Str. 9, 60438 Frankfurt, Germany.

Biochimica Et Biophysica Acta. Molecular Cell Research
|August 14, 2017
PubMed
Summary

Mitochondrial acyl carrier proteins (ACPMs) are crucial for fatty acid synthesis and complex I function. Their interaction with LYR motif proteins is vital for complex assembly and stability.

Keywords:
Cysteine desulfurase NFS1 complexFe-S cluster biogenesis, Lipoic acidMitochondrial acyl carrier proteinMitochondrial fatty acid synthesis type IIRespiratory complex I

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