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N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate

Danyi Lu1, Qian Xie2, Baojian Wu2

  • 1Research Center for Biopharmaceutics and Pharmacokinetics, College of Pharmacy, Jinan University, Guangzhou, China; Shenzhen Key Laboratory for Molecular Biology of Neural Development, Guangdong Key Laboratory of Nanomedicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, China.

Journal of Pharmaceutical and Biomedical Analysis
|August 14, 2017
PubMed

Keywords:
N-glucuronidationSpecies differencesTertiary aminesUGT1A4UGT2B10

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