Related Experiment Video
Updated: Feb 24, 2026

06:47
Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
9.9K
Should patients take vitamin D before mandibular operations?
N Syed1, G A Chiu1, P Korczak1
1Department of Oral and Maxillofacial Surgery, Royal Derby Hospital, Uttoxeter Road, Derby DE22 3NE, UK.
The British Journal of Oral & Maxillofacial Surgery
|August 15, 2017
Summary
Vitamin D deficiency is common in the UK. Screening and supplementation before mandibular surgery can prevent complications in at-risk patients.
Area of Science:
- Oral and Maxillofacial Surgery
- Nutritional Science
- Public Health
Background:
- Vitamin D deficiency is prevalent in the United Kingdom, affecting various patient demographics.
- Low vitamin D levels can be linked to complications following surgical procedures.
- Screening and supplementation are cost-effective interventions.
Purpose of the Study:
- To investigate the outcomes of patients with vitamin D deficiency undergoing mandibular fracture reduction or osteotomy.
- To evaluate the impact of preoperative screening and supplementation on surgical outcomes.
- To recommend screening and supplementation protocols for at-risk patients.
Main Methods:
- Retrospective review of patients with vitamin D deficiency undergoing mandibular procedures.
- Analysis of complication rates in patients with and without preoperative screening/supplementation.
- Cost-effectiveness analysis of vitamin D testing and supplementation.
Main Results:
- Patients with vitamin D deficiency experienced complications after mandibular fracture reduction and osteotomy.
- Preoperative screening identified at-risk individuals for vitamin D deficiency.
- Supplementation is inexpensive and can mitigate risks.
Conclusions:
- Preoperative screening for vitamin D deficiency is recommended for patients undergoing mandibular operations.
- Supplementation should be considered for patients at risk, especially those scheduled for orthognathic surgery or temporomandibular joint replacement.
- Addressing vitamin D deficiency is a crucial, cost-effective measure in oral and maxillofacial surgery.
Related Concept Videos
Role of Vitamins in Maintaining Bone Health
5.8K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.8K
Tonsillitis II: Management
480
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
480
Role of Skin in Vitamin D Synthesis
8.3K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.3K

