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Effect of oral contraceptives on balance in women: A randomized controlled trial
Ahmed M Maged1, Emad Salah1, Ahmed M Kamel1
1Obstetrics and Gynecology Department, Cairo University, Egypt.
Objective:
To detect the effect of combined oral contraceptive pills (COC) on dynamic postural balance in healthy middle aged women.
Materials And Methods:
A prospective randomized controlled study included 200 patients classified into two groups. Group I received COC containing 30 μg of EE and 3 mg of drospirenone for 12 consecutive cycles and Group II received no treatment. Overall, medio-lateral and antero-posterior stability were measured using Biodex system after 12 months.
Results:
There was a highly statistically significant difference between the 2 study groups regarding estradiol level (12.84 ± 1.96 vs. 38.86 ± 3.99, P value < 0.001) and progesterone level (0.52 ± 0.25 vs. 11.64 ± 4.53, P value < 0.001). There was a highly statistically significant difference between the 2 study groups regarding mediolateral stability (1.84 ± 0.23 vs. 2.40 ± 0.56, P value < 0.001), antereoposterior stability (1.91 ± 0.29 vs. 2.33 ± 0.61, P value < 0.001) or overall stability (2.42 ± 0.29 vs. 2.95 ± 0.53, P value < 0.001).
Conclusion:
COC are effective method of contraception to improve postural balance and decrease risk of injury in normal and athletic women. NCT02855294.
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