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Updated: Feb 24, 2026

Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
Published on: July 21, 2022
Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis
Jung Min Shim1, Jinhee Kim2, Tanel Tenson3
1Institut Pasteur Korea, Gyeonggi-do 13488, Korea. jungmin.shim@ip-korea.org.
Abstract:
Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new treatments are urgently needed. Developing new virus control modalities requires better understanding of virus-host interactions. Here, we describe how IAV infection triggers cellular apoptosis and how this process can be exploited towards the development of new therapeutics, which might be more effective than the currently available anti-influenza drugs.
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