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Brain Tuberculoma: A Case Report and Literature Review.
Khalil Aloreidi1, Jamal Dodin1, Jeremy Berg2
1Department of Internal Medicine, University of South Dakota Sanford School of Medicine.
Summary
This report details a rare case of central nervous system tuberculosis (TB) presenting as multiple brain tuberculomas in an immunocompetent patient. Diagnosis involved MRI and surgical excision, highlighting a unique presentation of this uncommon neurological infection.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Central nervous system tuberculosis (CNS TB) is a serious infection, often with varied clinical presentations.
- Tuberculomas, a less common manifestation of CNS TB, pose diagnostic challenges.
Observation:
- A 44-year-old immunocompetent male presented with headache and fever.
- Brain MRI revealed two ring-enhancing lesions, suggestive of an infectious or neoplastic process.
Findings:
- Surgical excision and histopathology confirmed the lesions as tuberculomas.
- This case represents a rare occurrence of multiple tuberculomas in South Dakota.
Implications:
- Highlights the importance of considering CNS TB in the differential diagnosis of brain lesions, even in low-prevalence areas.
- Emphasizes the role of advanced imaging and histopathology in diagnosing rare forms of neurological infections.
- Underscores the need for continued awareness and prompt treatment of CNS TB to prevent severe outcomes.

