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Antibacterial Effect of Provisional Cements with Incorporated Polyethyleneimine Nanoparticles: An In Vivo Study
Purpose:
Provisional restorations exhibit various degrees of microleakage when cemented. Incorporation of quaternized polyethyleneimine nanoparticles (QPEI) into provisional cements may be effective against bacteria in vivo.
Materials And Methods:
Nine polymethylmethacrylate provisional restorations in human volunteers were evaluated after cementation with and without QPEI nanoparticles. Bacterial load in the provisional cement was assessed after 1 week of cementation.
Results:
The number of colony-forming units in the cement with QPEI was significantly lower (P < .05) than in the control cement.
Conclusion:
The results of this in vivo study clearly indicate that provisional cement incorporating QPEI nanoparticles significantly reduces viable bacterial counts in the provisional cement in all patients.
