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Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Graphene- gold based nanocomposites applications in cancer diseases; Efficient detection and therapeutic tools
Lina A Al-Ani1, Mohammed A AlSaadi2, Farkaad A Kadir3
1Institute of Postgraduate Studies Building, Nanotechnology & Catalysis Research Centre (NANOCAT), University of Malaya, Kuala Lumpur 50603, Malaysia.
Abstract:
Early detection and efficient treatment of cancer disease remains a drastic challenge in 21st century. Throughout the bulk of funds, studies, and current therapeutics, cancer seems to aggressively advance with drug resistance strains and recurrence rates. Nevertheless, nanotechnologies have indeed given hope to be the next generation for oncology applications. According to US National cancer institute, it is anticipated to revolutionize the perspectives of cancer diagnosis and therapy. With such success, nano-hybrid strategy creates a marvelous preference. Herein, graphene-gold based composites are being increasingly studied in the field of oncology, for their outstanding performance as robust vehicle of therapeutic agents, built-in optical diagnostic features, and functionality as theranostic system. Additional modes of treatments are also applicable including photothermal, photodynamic, as well as combined therapy. This review aims to demonstrate the various cancer-related applications of graphene-gold based hybrids in terms of detection and therapy, highlighting the major attributes that led to designate such system as a promising ally in the war against cancer.
Insights
Graphene-gold hybrids offer new hope for cancer treatment and diagnosis. These nanomaterials show promise as advanced vehicles for drug delivery and theranostic systems in oncology.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Oncology
Background:
- Cancer remains a significant challenge, with drug resistance and recurrence limiting current treatments.
- Nanotechnology presents a promising next-generation approach for cancer diagnosis and therapy.
- Nano-hybrid strategies are gaining traction for their potential in oncology.
Purpose of the Study:
- To review the applications of graphene-gold based hybrids in cancer detection and therapy.
- To highlight the key attributes of these materials in combating cancer.
- To showcase their potential as theranostic systems.
Main Methods:
- Review of current literature on graphene-gold hybrid nanomaterials in oncology.
- Analysis of their performance in cancer diagnosis and therapeutic applications.
- Examination of their use in drug delivery, optical diagnostics, and combined therapies.
Main Results:
- Graphene-gold hybrids demonstrate robust performance as therapeutic agent vehicles.
- These composites possess inherent optical diagnostic capabilities.
- They function effectively as theranostic systems, integrating diagnosis and therapy.
Conclusions:
- Graphene-gold hybrids are emerging as powerful tools in cancer management.
- Their versatility supports applications in early detection and advanced treatment modalities.
- These nano-hybrids represent a promising strategy in the fight against cancer.
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