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Updated: Feb 24, 2026

Micro-scale Engineering for Cell Biology
Published on: October 1, 2007
Stem cell industry update: 2012 to 2016 reveals accelerated investment, but market capitalization and earnings lag
Mitchell Ng1, Simon Song2, Nicolas S Piuzzi3
1Cleveland Clinic, Department of Orthopedic Surgery, Cleveland, Ohio, USA.
Abstract:
Treatments based on stem cells have long been heralded for their potential to drive the future of regenerative medicine and have inspired increasing medical and business interest. The stem cell therapy market has been expanding since 2012, but earnings and profitability still lag the broader health care sector (compounded annual growth rate in annual financing of 31.5% versus 13.4%, respectively). On the basis of historical financial data, approximately $23 billion has been invested in stem cell companies since 1994, with more than 80% of this raised from 2011 through 2016. This reflects a marked acceleration in capital investment, as companies began late-stage clinical trials, initiate partnerships or are acquired by large pharmaceutical companies. All of these data reflect a field that is emerging from infancy, which will demand more time and capital to mature. This update is relevant to researchers, clinicians and investors who wish to quantify the potential in this field.
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