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ePlant: Visualizing and Exploring Multiple Levels of Data for Hypothesis Generation in Plant Biology
Jamie Waese1, Jim Fan2, Asher Pasha1
1Department of Cell and Systems Biology/Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Ontario M5S 3B2, Canada.
The Plant Cell
|August 16, 2017
Summary
ePlant is a new visual analytic tool that integrates multiple data types for Arabidopsis thaliana research. This platform simplifies complex data exploration, aiding hypothesis generation in systems biology.
Area of Science:
- Systems Biology
- Bioinformatics
- Plant Science
Background:
- Systems biology research faces challenges integrating diverse data from separate sources.
- Current workflows increase cognitive load, hindering hypothesis generation.
- A unified platform for integrated data access, search, analysis, and visualization is needed.
Purpose of the Study:
- To present ePlant, a visual analytic tool for exploring multiple levels of Arabidopsis thaliana data.
- To provide integrated search, analysis, and visualization features through a single portal.
- To facilitate hypothesis generation by reducing cognitive load in data exploration.
Main Methods:
- ePlant connects to public web services to download genome, proteome, interactome, transcriptome, and 3D molecular structure data.
- Data are visualized using a zoomable user interface and a conceptual hierarchy.
- The tool combines information from multiple data types within its visualization features.
Main Results:
- ePlant provides integrated access to diverse Arabidopsis thaliana data.
- The platform offers a user-friendly, zoomable interface for data exploration.
- Examples demonstrate ePlant's utility in generating hypotheses through integrative features.
Conclusions:
- ePlant addresses the need for a robust research platform in systems biology.
- The tool enhances hypothesis generation by simplifying complex data navigation.
- ePlant's code is freely available for adaptation to other biological species.
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