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Isolated Renal Mucormycosis in Immunocompetent Children: A Report of Two Cases
Sai Saran1, Kirti Naranje2, Mohan Gurjar1
1Department of Critical Care Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Abstract:
Isolated renal mucormycosis is a rare entity in children. It is potentially fatal when not detected and managed early with antifungal therapy, and surgery as and when needed. We present two immunocompetent children who developed this infection and subsequently succumbed to it. The diagnosis was established postmortem on renal biopsy specimens. We also discuss the 9 cases of isolated renal involvement in children published in literature.
Insights
Isolated renal mucormycosis is a rare and fatal fungal infection in children. Early diagnosis and treatment are crucial but challenging, as highlighted by two cases and a literature review.
Area of Science:
- Pediatric Nephrology
- Mycology
- Infectious Diseases
Background:
- Isolated renal mucormycosis is a rare but severe fungal infection affecting the kidneys.
- Prompt diagnosis and management, including antifungal therapy and surgery, are critical for patient survival.
Observation:
- This report details two immunocompetent children who developed isolated renal mucormycosis.
- Despite medical intervention, both children unfortunately succumbed to the infection.
Findings:
- Diagnosis in these cases was confirmed postmortem via renal biopsy.
- A review of existing literature identified nine previously reported cases of isolated renal mucormycosis in children.
Implications:
- This case series underscores the aggressive nature of renal mucormycosis in pediatric patients.
- Emphasizes the need for heightened clinical suspicion and rapid diagnostic approaches for this rare condition in children.
