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Related Concept Videos

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Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Related Experiment Video

Updated: Feb 24, 2026

In situ Transverse Rectus Abdominis Myocutaneous Flap: A Rat Model of Myocutaneous Ischemia Reperfusion Injury
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Rectus Sheath Hematoma Associated with Apixaban.

Kulothungan Gunasekaran1, Amanda R McFee Winans2, Swetha Murthi3

  • 1Division of Hospital Medicine, Henry Ford Hospital, Detroit, MI, USA.

Clinics and Practice
|August 16, 2017
PubMed
Summary
This summary is machine-generated.

Apixaban, a Factor Xa inhibitor, can rarely cause rectus sheath hematoma. Early recognition and management are crucial for this serious bleeding complication in patients on anticoagulation.

Keywords:
Rectus sheath hematomaanticoagulationapixaban

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Area of Science:

  • Pharmacology
  • Hematology
  • Medical Case Reports

Background:

  • Apixaban is a direct Factor Xa inhibitor used for deep venous thrombosis (DVT) and stroke prevention in non-valvular atrial fibrillation.
  • Rectus sheath hematoma is a rare but potentially life-threatening complication associated with anticoagulant therapy.

Observation:

  • An elderly patient on apixaban for DVT treatment presented with severe abdominal pain.
  • Computed tomography (CT) confirmed a left rectus sheath hematoma.

Findings:

  • Apixaban was discontinued, and the patient was monitored.
  • The rectus sheath hematoma resolved completely within one month, as confirmed by outpatient CT.

Implications:

  • Clinicians should be aware of rare, serious bleeding risks associated with anticoagulants like apixaban.
  • Prompt recognition and management are essential for adverse bleeding events, including rectus sheath hematoma.