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Related Concept Videos

Heart Failure I: Introduction01:27

Heart Failure I: Introduction

1.0K
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
1.0K
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

467
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
467
Heart Failure Drugs: Diuretics01:22

Heart Failure Drugs: Diuretics

1.1K
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
1.1K
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

4.1K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.1K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.1K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.1K
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

576
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
576

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Related Experiment Video

Updated: Feb 24, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

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Vitamin D and Heart Failure.

D Marshall Brinkley1, Omair M Ali1, Sandip K Zalawadiya1

  • 1Division of Cardiovascular Medicine, Vanderbilt University Medical Center, 2220 Pierce Avenue; Preston Research Building, Suite 383, Nashville, TN, 37232-6300, USA.

Current Heart Failure Reports
|August 16, 2017
PubMed
Summary
This summary is machine-generated.

Low vitamin D status is linked to heart failure risk and outcomes. However, current evidence is insufficient to recommend vitamin D supplementation for preventing or treating chronic heart failure.

Keywords:
Cardiovascular diseaseHeart failureOutcomesVitamin D

Related Experiment Videos

Last Updated: Feb 24, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

11.2K

Area of Science:

  • Cardiology
  • Endocrinology
  • Nutritional Science

Background:

  • Vitamin D is crucial for calcium homeostasis.
  • Preclinical studies suggest vitamin D influences cardiovascular function and heart failure risk.
  • Many individuals with cardiovascular disease exhibit low vitamin D levels, presenting a potential therapeutic target.

Purpose of the Study:

  • To review the rationale for vitamin D supplementation in heart failure.
  • To explore the potential role of vitamin D in preventing and treating chronic heart failure.

Main Methods:

  • Review of preclinical studies.
  • Analysis of observational evidence linking vitamin D status to heart failure.
  • Evaluation of existing clinical trials on vitamin D supplementation in heart failure.

Main Results:

  • Observational studies associate low vitamin D with increased heart failure risk, ventricular remodeling, and mortality.
  • Clinical trials on vitamin D supplementation for heart failure have been small and inconclusive.
  • Insufficient data exists to support routine vitamin D assessment or supplementation for heart failure.

Conclusions:

  • While observational data is compelling, clinical trial evidence is lacking.
  • Further large-scale, prospective trials powered for clinical outcomes are necessary.
  • Current evidence does not support routine vitamin D supplementation for heart failure prevention or treatment.