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Updated: Feb 24, 2026

Clarifying and Imaging Candida albicans Biofilms
Published on: March 6, 2020
Microbe Profile: Candida albicans: a shape-changing, opportunistic pathogenic fungus of humans
1The Aberdeen Fungal Group, MRC Centre for Medical Mycology, School of Medicine, Medical Science and Nutrition, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB252ZD, UK.
Abstract:
Candida albicans is normally a harmless commensal of human beings, but it can cause superficial infections of the mucosa (oral/vaginal thrush) in healthy individuals and (rarely) infections of the skin or nails. It can also become invasive, causing life-threatening systemic and bloodstream infections in immunocompromised hosts, where the mortality rate can be as high as 50 %. It is the most common cause of serious fungal infection and is a common cause of nosocomial infections in hospitals. Some strains have been recognized that are resistant to azoles or echinocandins, which are the first-line antifungals for treatment of C. albicans infections.
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