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Screening performance for callosal agenesis in prenatal life. Single center study
Hubert Huras1, Magdalena Nowak1, Izabela Herman-Sucharska2
1Jagiellonian University Collegium Medicum, Department of Obstetrics and Perinatology, Kopernika 23 Street, 31-501 Krakow, Poland.
Objectives:
1) To analyze screening performance of second trimester scan for ACC, 2) to evaluate the agreement between ultrasound and MRI and 3) to compare prenatal and postnatal diagnosis.
Methods:
It was a prospective observational study. All patients with fetuses suspected of ACC were referred to prenatal MRI (pMRI).
Results:
One subject was not confirmed by pMRI with the diagnosis of ACC. This case demonstrated partial ACC in neonatal MRI (nMRI).
Conclusion:
Sensitivity of second trimester scan for callosal agenesis of 73% and specificity of 99%. Prenatal MRI and US has similar amount of misdiagnoses.
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