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Updated: Feb 24, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Sensorimotor rhythm neurofeedback as adjunct therapy for Parkinson's disease
Ingrid H C H M Philippens1,2, Jacqueline A Wubben2, Raymond A P Vanwersch1
1Animal Science Department Biomedical Primate Research Centre (BPRC) P.O. Box 3306 Rijswijk 2280 GH the Netherlands.
Abstract:
Neurofeedback may enhance compensatory brain mechanisms. EEG-based sensorimotor rhythm neurofeedback training was suggested to be beneficial in Parkinson's disease. In a placebo-controlled study in parkinsonian nonhuman primates we here show that sensorimotor rhythm neurofeedback training reduces MPTP-induced parkinsonian symptoms and both ON and OFF scores during classical L-DOPA treatment. Our findings encourage further development of sensorimotor rhythm neurofeedback training as adjunct therapy for Parkinson's disease which might help reduce L-DOPA-induced side effects.
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