Use of bilayer matrix wound dressing in the exenterated socket
Leon Rafailov1, Roger E Turbin1, Paul D Langer1
1a Institute of Ophthalmology and Visual Science , Rutgers New Jersey Medical School , Newark, New Jersey , USA.
Orbit (Amsterdam, Netherlands)
|August 17, 2017
Summary
This study shows Integra bilayer dermal substitute effectively reconstructs exenterated orbits. The graft ensures rapid epithelialization and minimal complications, offering a superior alternative for orbital reconstruction.
Area of Science:
- Ophthalmology
- Plastic Surgery
- Biomaterials Science
Background:
- Orbital exenteration, the removal of orbital contents, necessitates complex reconstruction.
- Traditional reconstruction methods like skin grafting or free flaps have limitations.
Purpose of the Study:
- To evaluate the efficacy of Integra bilayer dermal substitute for lining exenterated orbits.
- To assess graft integration, epithelialization, and patient outcomes.
Main Methods:
- Retrospective chart review of 7 patients undergoing orbital exenteration and reconstruction with Integra bilayer.
- Data collected included demographics, pathology, complications, graft integrity, and patient acceptance.
Main Results:
- Successful graft integration observed in all cases by 3-4 weeks post-surgery.
- Rapid and uncomplicated socket epithelialization occurred within weeks.
- No intraoperative or postoperative complications were reported.
Conclusions:
- Integra bilayer dermal substitute is an effective and ideal graft for exenterated orbit reconstruction.
- It offers advantages in ease of use, rapid healing, and minimal morbidity compared to other techniques.


