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Cannabinoids as therapeutic for PTSD.

Mallory Je Loflin¹, Kimberly A Babson¹, Marcel O Bonn-Miller²

¹National Center for PTSD, VA Palo Alto Health Care System, USA.

Current Opinion in Psychology

|August 17, 2017

Summary

Current treatments for post-traumatic stress disorder (PTSD) are limited. This review explores research on cannabinoids as a potential new therapy for PTSD symptoms, examining experimental, preclinical, and clinical findings.

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Area of Science:

Neurobiology
Pharmacology
Psychiatry

Background:

Current pharmacotherapies for post-traumatic stress disorder (PTSD) demonstrate limited efficacy.
Neurobiological research suggests cannabinoids may hold therapeutic potential for PTSD.
There is increasing public interest in using cannabinoids for trauma symptom relief.

Purpose of the Study:

To provide an updated review of current research on the therapeutic value of cannabinoids for PTSD.
To synthesize findings from experimental, preclinical, and clinical studies.

Main Methods:

Literature review of experimental, preclinical, and clinical studies.
Analysis of neurobiological evidence.
Examination of observational reports on cannabinoid use for trauma.

Main Results:

The review synthesizes current research findings on cannabinoids and PTSD.
Evidence from various study types is discussed to evaluate therapeutic potential.

Conclusions:

Cannabinoids represent a promising area for future pharmacological treatments for PTSD.
Further research is warranted to fully understand the therapeutic efficacy and safety of cannabinoids for PTSD.