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Hematologic, Biochemical, and Endocrine Parameters in Horses With Tooth Resorption and Hypercementosis
Edward T Earley1,2,3, Jennifer R Rawlinson4, Robert M Baratt5
11 Department of Clinical Sciences, Cornell University, Ithaca, NY, USA.
Journal of Veterinary Dentistry
|August 18, 2017
Summary
Equine odontoclastic tooth resorption and hypercementosis (EOTRH) in horses showed no significant hematologic, biochemical, or endocrine changes. Hypoalbuminemia was the most common finding, but parathyroid hormone levels require further investigation with control groups.
Area of Science:
- Veterinary Medicine
- Equine Dentistry
- Endocrinology
Background:
- Equine odontoclastic tooth resorption and hypercementosis (EOTRH) is a common dental disease in adult horses.
- The etiology of EOTRH remains unknown.
- Limited data exists on hematologic, biochemical, and endocrine values in horses with EOTRH.
Purpose of the Study:
- To characterize hematologic, biochemical, and endocrine parameters in horses diagnosed with EOTRH.
- To identify potential laboratory abnormalities associated with EOTRH.
Main Methods:
- Descriptive cross-sectional study involving client-owned horses with EOTRH.
- Diagnosis confirmed via oral examination, radiography, and histopathology.
- Complete blood count, biochemistry panel, and endocrine profile were analyzed.
Main Results:
- Hypoalbuminemia was observed in 88% of EOTRH-affected horses.
- Thyroid and pituitary pars intermedia function appeared normal.
- Elevated parathyroid hormone was noted in 47% of horses, with 17% showing elevated 25-hydroxy vitamin D.
Conclusions:
- No definitive hematologic, biochemical, or endocrine abnormalities were identified in this small EOTRH population.
- The significance of elevated parathyroid hormone requires further study with age-matched controls.
- Additional research with larger, controlled populations is needed to understand EOTRH-associated laboratory trends.
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