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Bronchiolitis Care in the Hospital
Jennifer Orr Vincent1, Huay-Ying Lo2, Susan Wu3
1Division of Pediatrics and Adolescent Medicine, University of North Carolina 231 MacNider, CB#7225 Chapel Hill, NC 27599. United States.
Insights
Supportive care is the primary treatment for viral bronchiolitis in children. Evidence does not support routine use of bronchodilators, corticosteroids, or antibiotics, focusing instead on hydration and oxygen therapy.
Area of Science:
- Pediatrics
- Infectious Diseases
- Respiratory Medicine
Background:
- Viral bronchiolitis is a frequent reason for pediatric hospitalization.
- Current treatments often focus on supportive care, despite various therapeutic options.
Purpose of the Study:
- To review current evidence on supportive and pharmacologic treatments for hospitalized bronchiolitis patients.
- To inform clinical practice regarding effective bronchiolitis management.
Main Methods:
- Conducted a MEDLINE search with a medical librarian.
- Focused on publications concerning bronchiolitis management and therapies.
Main Results:
- Bronchodilators, epinephrine, corticosteroids, and antibiotics lack evidence for routine use.
- Hypertonic saline may benefit select patients; continuous pulse oximetry is not routinely recommended.
- Supplemental oxygen targets are ≥90% oxyhemoglobin; high-flow nasal cannula may reduce intubation.
- Intravenous or nasogastric hydration is indicated for insufficient oral intake.
Conclusions:
- Bronchiolitis is a self-limited viral illness.
- Supportive care remains the cornerstone of bronchiolitis treatment.
- Evidence-based guidelines support conservative management strategies.
Background:
Viral bronchiolitis is a common cause of hospitalization in young children, but despite a variety of therapeutic options, the mainstay of treatment remains supportive care.
Objective:
To examine the most recent evidence for supportive care measures and pharmacologic options in the treatment of bronchiolitis in the hospital setting.
Method:
MEDLINE search with expert medical librarian for publications on management and therapies for bronchiolitis.
Results:
Evidence does not support the use of bronchodilators, racemic epinephrine, deep suctioning, systemic corticosteroids, or antibiotics in the absence of a concomitant bacterial infection, as these treatments do not change the course of illness or shorten length of stay (LOS). Nebulized hypertonic saline is not routinely recommended, though it may provide some benefit for patients with anticipated prolonged LOS. Continuous pulse oximetry should not be routinely used in stable patients as it may be associated with longer LOS. Supplemental oxygen should be used to maintain oxyhemoglobin concentrations ≥90%, a level lower than what many clinicians may have used previously. Current evidence suggests high-flow nasal cannula may reduce intubation rate, but its effect on LOS is unclear. Intravenous or nasogastric tube hydration should be used when oral hydration is not sufficient.
Conclusion:
Overall, bronchiolitis remains a self-limited disease whose mainstay of therapy is supportive care.
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