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Infant feeding patterns and eczema in children in the first 6 years of life
N Soto-Ramírez1, S Kar2, H Zhang2
1College of Social Work, University of South Carolina, Columbia, SC, USA.
Insights
Mixed infant feeding, including pumping and formula, may increase eczema risk compared to direct breastfeeding. Further research is needed to assess allergy risks associated with various infant feeding modes.
Area of Science:
- Pediatrics
- Allergology
- Public Health
Background:
- Infant feeding practices significantly influence child health outcomes.
- Understanding the relationship between feeding modes and allergies is crucial for early intervention.
Purpose of the Study:
- To evaluate the risk of eczema/skin allergy up to age 6 years associated with different infant feeding patterns in the first 6 months.
- To compare these risks against direct breastfeeding for at least 3 months.
Main Methods:
- Utilized data from the Infant Feeding Practices Study II (US) with a 6-year follow-up.
- Analyzed feeding modes and doctor-diagnosed eczema/skin allergy in 1387 infants via parental reports.
- Employed log-linear models to calculate prevalence ratios (PRs) adjusting for confounders.
Main Results:
- Mixed feeding (direct breast, pumped breast milk, formula) showed a significantly higher risk of eczema/skin allergy (PR=1.46).
- Direct breastfeeding combined with mixed feeding also indicated increased risk (PR=1.26), though not statistically significant.
- Exclusive formula feeding from birth did not impact eczema risk; paternal eczema and Hispanic ethnicity were risk factors.
Conclusions:
- Mixed infant feeding patterns may elevate the risk of developing eczema/skin allergy.
- The increasing trend of mixed feeding and pumping necessitates further investigation into allergy risks.
- Evidence supports the need for updated guidance on infant feeding modes and allergy prevention.
Background:
Modes of infant feeding such as direct and indirect breastfeeding, and formula feeding, and their combinations may play a role in child health.
Objective:
The aim was to investigate which feeding patterns in the first 6 months pose risks of eczema/skin allergy in children up to 6 years compared to direct breastfeeding for at least 3 months.
Methods:
The Infant Feeding Practices Study II in the United States and its 6-year follow-up provided data on feeding modes in infancy and doctor's diagnosed eczema/skin allergy in the first 6 years of life (1387 infants), based on parental reports. Different feeding patterns were identified. Log-linear models were used to estimate prevalence ratios (PRs) of feeding patterns for doctor's diagnosed eczema/skin allergy in the first 6 years of life, adjusting for confounders.
Results:
Compared to "direct breastfeeding for at least 3 months" (DBF3m), the combination of "direct feeding at the breast (DBF), pumping and feeding breast milk (BM), and formula (FF) in the first months" (DBF/BM/FF) showed a statistically significant higher risk of eczema/skin allergy in the first 6 years of life (PR = 1.46), adjusting for confounders. DBF combined with BM for the first 3 months followed by mixed feeding also had an increased risk (PR = 1.26), although not statistically significant. Formula feeding introduced since birth had no effect on eczema. Among the confounders, paternal eczema and race/ethnicity (Hispanic vs White) were associated with a higher risk of eczema/skin allergy.
Conclusions & Clinical Relevance:
Mixed infant feeding may carry a higher risk of eczema/skin allergy compared to direct feeding at the breast. The recent epidemic of pumping and feeding in the United States and the use of mixed infant feeding modes requires additional studies to provide appropriate and renewed assessments of the risks of feeding modes for the future development of allergies.
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