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Two-stage hepatectomy for multiple giant alveolar echinococcosis
Hao-De Shen1, Ke-Fei Chen, Bo Li
1Department of Liver Surgery and Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu Hydatid Disease Institute of Ganzi Prefecture, Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China.
Medicine
|August 18, 2017
Summary
Two-stage hepatectomy is a safe and effective treatment for multiple giant alveolar echinococcosis when complete removal is challenging. This approach allows for liver regeneration, improving outcomes for patients with this serious parasitic liver disease.
Area of Science:
- Hepatobiliary Surgery
- Parasitic Diseases
- Surgical Oncology
Background:
- Alveolar echinococcosis is a severe, progressive liver disease with poor prognosis if radical resection is not possible.
- Limited future remnant liver volume can preclude curative resection in patients with multiple giant alveolar echinococcosis.
Purpose of the Study:
- To evaluate the safety and feasibility of two-stage hepatectomy for multiple giant alveolar echinococcosis.
- To assess the efficacy of staged liver resection in managing complex cases of alveolar echinococcosis.
Main Methods:
- Retrospective review of patients who underwent two-stage hepatectomy for multiple giant alveolar echinococcosis between August 2013 and December 2015.
- Analysis of surgical outcomes, including mortality, recurrence, and follow-up duration, for seven identified patients.
Main Results:
- Seven patients successfully completed two-stage hepatectomy.
- First-stage hepatectomy involved either right-sided (4 patients) or left-sided (3 patients) resection.
- Second-stage hepatectomy was performed 3 months post-first stage, with no operation-related mortality or disease recurrence after >1 year follow-up.
Conclusions:
- Two-stage hepatectomy is a safe and feasible surgical strategy for managing multiple giant alveolar echinococcosis.
- Staged liver resection can overcome limitations of remnant liver volume, enabling curative treatment for complex cases.
