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Owlready: Ontology-oriented programming in Python with automatic classification and high level constructs for

Jean-Baptiste Lamy1

  • 1LIMICS, Université Paris 13, Sorbonne Paris Cité, 93017 Bobigny, INSERM UMRS 1142, UPMC Université Paris 6, Sorbonne Universités, Paris, France.

Artificial Intelligence in Medicine
|August 19, 2017
PubMed
Summary
This summary is machine-generated.

Owlready is a Python module that simplifies accessing and manipulating biomedical ontologies. It offers high-level programming constructs for easier class management and local closed-world reasoning, enhancing ontology-oriented programming.

Keywords:
Automatic classificationBiomedical ontologyLocal closed world reasoningOWLOntology-oriented programmingSemantic web

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Area of Science:

  • Biomedical Informatics
  • Computational Biology
  • Knowledge Representation

Background:

  • Ontologies are crucial in the biomedical domain, but existing programming interfaces (e.g., SPARQL, OWLAPI) lack ease of use for object-oriented programming.
  • Difficulties in manipulating classes as easily as individuals and the open-world assumption of ontologies pose challenges for biomedical reasoning.

Purpose of the Study:

  • To design a user-friendly Python module for accessing and modifying OWL ontologies.
  • To provide high-level constructs specifically tailored for the complexities of biomedical ontologies.

Main Methods:

  • Developed Owlready, a Python module enabling ontology-oriented programming.
  • Integrated the OWL ontology model with the Python object model for seamless access.
  • Implemented a high-level syntax for managing classes and role-filler constraints.
  • Developed an algorithm for local closed-world reasoning.

Main Results:

  • Owlready (version 2) provides a high-level interface for OWL ontologies within Python.
  • Demonstrated ease of use with examples from Gene Ontology (GO).
  • Successfully applied Owlready in a use case comparing drug contraindications, showcasing class manipulation and closed-world reasoning.

Conclusions:

  • Owlready offers a practical solution for ontology programming in the biomedical field.
  • The module is open-source and has been adopted in medical research.
  • Future work includes support for vagueness and advanced reasoning features.