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Updated: Feb 24, 2026

Cerenkov Luminescence Imaging CLI for Cancer Therapy Monitoring
Published on: November 13, 2012
Monte Carlo simulations support non-Cerenkov radioluminescence production in tissue
Nicole L Ackerman1, Federico Boschi2, Antonello E Spinelli3
1Agnes Scott College, Department of Physics and Astronomy, Decatur, Georgia, United States.
Abstract:
There is experimental evidence for the production of non-Cerenkov radioluminescence in a variety of materials, including tissue. We constructed a Geant4 Monte Carlo simulation of the radiation from P32 and Tc99m interacting in chicken breast and used experimental imaging data to model a scintillation-like emission. The same radioluminescence spectrum is visible from both isotopes and cannot otherwise be explained through fluorescence or filter miscalibration. We conclude that chicken breast has a near-infrared scintillation-like response with a light yield three orders of magnitude smaller than BGO.

