Related Experiment Video
Updated: Feb 24, 2026
03:40
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
1.6K
Medications and Adverse Voice Effects
Kátia Nemr1, Ariana Di Carlos Silva1, Danilo de Albuquerque Rodrigues1
1Faculdade de Medicina-Universidade de São Paulo, Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo, Brazil.
Journal of Voice : Official Journal of the Voice Foundation
|August 21, 2017
Summary
Medications can directly and indirectly impact voice production, leading to symptoms like dry throat and shortness of breath. These vocal side effects are linked to medication use and dysphonia severity.
Area of Science:
- Otolaryngology
- Speech-Language Pathology
- Pharmacology
Background:
- Dysphonia, or impaired voice production, affects numerous individuals.
- Medication side effects are a potential, yet often overlooked, contributing factor to voice disorders.
- Understanding these medication effects is crucial for comprehensive patient care.
Purpose of the Study:
- To identify medications used by patients with dysphonia.
- To describe voice symptoms and evaluate medication effects on voice production.
- To determine associations between adverse voice effects and patient characteristics.
Main Methods:
- Retrospective cross-sectional study of 55 patients.
- Evaluation of vocal signs and symptoms using the Dysphonia Risk Protocol.
- Analysis of medication use, hydration, smoking, comorbidities, and vocal parameters.
Main Results:
- 73 active ingredients were identified; 8.2% had direct and 91.8% indirect vocal effects.
- Associations found between direct adverse voice effects and self-reported symptoms (dry throat, shortness of breath).
- Vocal deviation and pitch deviation correlated with direct medication side effects.
Conclusions:
- Medications significantly impact voice production through direct and indirect effects.
- Dry throat and shortness of breath are key symptoms associated with direct vocal side effects.
- Adverse vocal effects correlate with the degree of dysphonia and vocal deviation.
Related Concept Videos
01:25Antiasthma Drugs: β2-Adrenoceptor Agonists
1.8K
Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
1.8K
01:17Sedatives and Hypnotics Drugs: Miscellaneous Agents
689
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
689
01:30Drug toxicity: Drug–Drug Interaction
80
Drug–drug interactions can precipitate toxicity through multiple mechanisms. Absorption interactions alter how drugs enter the body, exemplified when ranitidine increases the absorption of basic drugs, while cholestyramine decreases the levels of propranolol. Protein binding interactions occur when drugs share the same binding sites on plasma proteins. Drugs like aspirin and warfarin, when bound in excess, can lead to increased free drug concentrations, enhancing the potential for...
80
01:27Effects of Chemicals: Overview
2.3K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
2.3K
01:21Skeletal Muscle Relaxants: Adverse Effects
930
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
Unlike...
930
01:24Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
2.1K
Adrenergic stimulation generally impacts cardiac rate and rhythm. Specifically, stimulation of the β-adrenoceptors triggers an increase in intracellular calcium ion influx and pacemaker currents, which may cause arrhythmias. Catecholamines like adrenaline also demonstrate β2-adrenoceptor-mediated hypokalemia, impacting cardiac action potential and disrupting the normal cardiac rhythm. Class II antiarrhythmic drugs are β-adrenoceptor antagonists or β-blockers, which...
2.1K