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Updated: Feb 24, 2026

Author Spotlight: Advancing Spectral Characterization of Physiological and Malperfused Tissues
Published on: July 5, 2024
Mesenteric Malperfusion: The Insidious, Dreadful Enemy
Akiko Tanaka1, Anthony L Estrera1
1Department of Cardiothoracic and Vascular Surgery, McGovern Medical School at The University of Texas Health Science Center at Houston and Memorial Hermann Hospital, Houston, Texas.
Abstract:
Mesenteric malperfusion is associated with a poor prognosis. Stent grafting to treat acute type B dissection with malperfusion has been widely accepted. The standard approach for acute type A dissection is central repair. However, mesenteric ischemia may continue to deteriorate. Can an algorithm with fenestration first approach improve the outcomes?
Insights
Mesenteric malperfusion, a complication of aortic dissection, can be treated with a fenestration-first approach. This strategy may improve outcomes for patients with acute type A dissection and mesenteric ischemia.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Aortic Dissection
Background:
- Mesenteric malperfusion significantly worsens prognosis in patients with aortic dissection.
- Stent grafting is a common treatment for acute type B dissection with malperfusion.
- Standard central repair for acute type A dissection does not always resolve ongoing mesenteric ischemia.
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