Moderate Psoriasis: A Proposed Definition

Area of Science:

• Dermatology
• Clinical assessment
• Psoriasis research

Background:

• The Psoriasis Area Severity Index (PASI) is standard for assessing psoriasis severity and guiding treatment.
• Current stratification divides patients into mild and moderate-to-severe disease categories based on PASI scores.

Purpose of the Study:

• To propose a refined definition and characterization of moderate psoriasis.
• To integrate PASI and Dermatology Life Quality Index (DLQI) scores for a more comprehensive assessment.

Main Methods:

• A consensus proposal was developed by 6 experienced dermatologists.
• Methods included a critical review of existing literature and case discussions.

Main Results:

• PASI, DLQI, and Body Surface Area (BSA) are recommended for classifying psoriasis severity (mild, moderate, severe).
• Severity assessment should combine PASI and DLQI, with equal weighting.
• Proposed criteria: Mild (PASI<7, DLQI<7), Moderate (PASI 7-15, DLQI 5-15, considering site/psychosocial impact), Severe (PASI >15).

Conclusions:

• A more precise psoriasis severity classification enhances risk-benefit assessment for therapeutic decisions.
• This refined classification aids in optimizing patient management and treatment strategies.