Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

431
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
431

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An imaging biomarker to detect non-glucogenic shift in brain energy metabolism in Alzheimer's disease.

Journal of translational medicine·2026
Same author

Proton MRI and MRSI as a Superior Methodology to Assess Oxidative Phosphorylation.

Academic radiology·2025
Same author

Association of Intracellular Microstructural and Neuropsychological Changes in HIV: A Pilot Validation of Trace Diffusion-Weighted Magnetic Resonance Spectroscopic Imaging Using Radial Trajectories.

Metabolites·2025
Same author

Quantification of Tryptophan and NAD<sup>+</sup> Proton Magnetization Exchange With Water Using Downfield <sup>1</sup>H MRS in the Human Brain at 7 T.

Magnetic resonance in medicine·2025
Same author

Reduction of radiofrequency induced implant heating via flexible metasurface shielding at 7 T.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2025
Same author

In Vivo Brain B<sub>1</sub> <sup>+</sup> Inhomogeneity Correction and NOE Image Enhancement at 7 T via Flexible Metasurfaces.

NMR in biomedicine·2025

Related Experiment Video

Updated: Feb 24, 2026

Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods
05:07

Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods

Published on: September 6, 2024

793

Multi-Echo-Based Echo-Planar Spectroscopic Imaging Using a 3T MRI Scanner.

Jon K Furuyama1, Brian L Burns1,2, Neil E Wilson1

  • 1Department of Radiological Sciences, University of California, Los Angeles, CA 90095, USA.

Materials (Basel, Switzerland)
|August 22, 2017
PubMed
Summary
This summary is machine-generated.

Multi-echo Echo-Planar Spectroscopic Imaging (MEEPSI) enhances spatial resolution by using spin-echoes to collect more data per scan. This improved resolution aids metabolite quantification in vivo despite minor spectral resolution trade-offs.

Keywords:
echo-planar spectroscopic imagingmulti-echo

More Related Videos

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.9K
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.9K

Related Experiment Videos

Last Updated: Feb 24, 2026

Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods
05:07

Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods

Published on: September 6, 2024

793
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.9K
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.9K

Area of Science:

  • Magnetic Resonance Imaging
  • Spectroscopy
  • Biomedical Engineering

Background:

  • Echo-Planar Spectroscopic Imaging (EPSI) is a rapid MRI technique.
  • Acquiring multiple phase-encoded lines per TR can improve efficiency.
  • Spin-echoes are sensitive to T₂ decay, impacting signal amplitude.

Purpose of the Study:

  • To investigate the impact of Multi-Echo-based Echo-Planar Spectroscopic Imaging (MEEPSI) on spatial resolution.
  • To assess the feasibility of using MEEPSI for in vivo metabolite quantification.

Main Methods:

  • Implementation of a MEEPSI sequence utilizing spin-echoes.
  • Acquisition of multiple phase-encoded lines within a single TR.
  • Analysis of Point Spread Function (PSF) Full Width at Half Maximum (FWHM) and 1D spatial profiles.
  • In vivo metabolite quantification using the LCModel fitting algorithm.

Main Results:

  • MEEPSI demonstrated a decrease in PSF FWHM, indicating improved spatial resolution.
  • Improved spatial resolution was validated using N-Acetyl Aspartate (NAA) in a gray matter phantom.
  • In vivo, T₂* decay effects on peak broadening were more significant than spectral resolution loss.
  • Metabolite quantification using LCModel remained feasible despite spectral resolution trade-offs.

Conclusions:

  • MEEPSI offers enhanced spatial resolution without increasing scan time.
  • The technique is suitable for in vivo metabolite quantification, as T₂* effects are dominant.
  • MEEPSI represents a valuable advancement for spectroscopic imaging applications.