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Does Circumcision Increase Meatal Stenosis Risk?-A Systematic Review and Meta-analysis
Brian J Morris1, John N Krieger1
1School of Medical Sciences and Bosch Institute, University of Sydney, Sydney, New South Wales, Australia; University of Washington School of Medicine, Department of Urology, Seattle, WA.
Urology
|August 23, 2017
Summary
The risk of meatal stenosis (MS) after male circumcision is low, under 1%. Applying petroleum jelly after circumcision significantly reduces this risk, suggesting a preventive measure.
Area of Science:
- Urology
- Pediatric Surgery
Background:
- Meatal stenosis (MS) is a recognized potential complication following male circumcision.
- The precise magnitude of risk associated with MS after circumcision remains a subject of debate.
Purpose of the Study:
- To systematically review and meta-analyze data on MS following circumcision.
- To assess the association between circumcision and MS.
- To evaluate preventive strategies for MS.
Main Methods:
- Comprehensive literature search of PubMed, Google Scholar, and Cochrane Library.
- Inclusion of studies with original data on MS in circumcised males of any age.
- Independent data extraction and study design verification by two reviewers.
Main Results:
- A meta-analysis of 27 studies (1,498,536 males) indicated a low MS risk of 0.656% post-circumcision.
- Observational studies showed a non-significantly higher MS prevalence in circumcised males (OR 3.20).
- Randomized controlled trials demonstrated that petroleum jelly application reduced MS risk (RR 0.024).
Conclusions:
- The incidence of MS following male circumcision is low (<1%).
- There is limited evidence suggesting a potentially higher MS prevalence in circumcised individuals.
- Petroleum jelly application emerges as an effective method to mitigate MS risk.
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