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Updated: Feb 24, 2026

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
ARTEFACTUALLY DAMPENED FLASH STIMULUS VISUAL EVOKED RESPONSES IN A SILICONE OIL-FILLED EYE
Ramesh Venkatesh1, Shailja Tibrewal2, Prachi Gurav1
1Department of Retina & Vitreous, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi; and.
Purpose:
To report a case of falsely dampened visual evoked responses in a patient of Usher syndrome after retinal detachment surgery secondary to probable intraocular silicone oil.
Methods:
Retrospective observational case report.
Case Description:
A 16-year-old boy with Usher syndrome developed rhegmatogenous retinal detachment in the left eye. He underwent a successful retinal detachment surgery with silicone oil tamponade. On his postoperative follow-up visit, poor vision was noted by our optometrist. A flash stimulus visual evoked response was done, which showed marked delayed latency and reduced amplitude. Marked improvement in the flash stimulus visual evoked response potentials and waveforms was noted after silicone oil removal.
Conclusion:
Intraocular silicone oil could be responsible for this false delay in the latency and reduction in flash stimulus visual evoked response amplitudes. Assessment of flash stimulus visual evoked responses in the presence of silicone oil after vitreoretinal surgery may produce unreliable responses.

