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Updated: Feb 24, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Nontraumatic adrenal hemorrhage: the adrenal stress
Marco Di Serafino1, Rosa Severino1, Valeria Coppola1
1Radiology Department, San Carlo Hospital, Potito Petrone St, 85100 Potenza, Italy.
Abstract:
Bilateral adrenal hemorrhage is a rare condition, which is burdened by potentially life-threatening consequences related to the development of acute adrenal insufficiency. Despite treatment with stress-dose glucocorticoids, a mortality rate of 15% has been reported, which varies according to the severity of underlying predisposing illness and could be much more higher if the adrenal insufficiency is not promptly recognized. An early diagnosis is crucial, though, because of nonspecific clinical and laboratory findings, adrenal hemorrhage is rarely suspected. Therefore, imaging has a pivotal role for the diagnosis of this uncommon condition but, despite adrenal hematomas characteristically appear round or oval with peripheral fat stranding, their initial presentation could be ambiguous. The authors describe a case of postoperative bilateral adrenal hemorrhage initially presenting at computed tomography scan as thickening of both glands surrounded by fat stranding, which led to close monitoring of adrenal function before unequivocal hemorrhage developed.
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