Related Experiment Video

Updated: Feb 24, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
06:51

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research

Published on: October 20, 2023

1.7K

New considerations in the assessment of aortic stenosis

Lucy M Safi1, Jonathan J Passeri2, Michael H Picard3

  • 1Director of Interventional Echocardiography, Hackensack University Medical Center, Hackensack, NJ 07601, USA.

Future Cardiology
|August 23, 2017
PubMed

Insights

Calcific aortic stenosis (AS) is a common heart valve disease. Future assessment will integrate advanced imaging, biomarkers, and genetics for better patient risk stratification.

Area of Science:

  • Cardiology
  • Valvular Heart Disease
  • Medical Diagnostics

Background:

  • Calcific aortic stenosis (AS) is a prevalent acquired valvular heart disease in industrialized nations.
  • The aging population is increasing the prevalence of AS.
  • Current preventative medications for AS have proven unsuccessful.

Purpose of the Study:

  • To explore advancements in identifying and risk-assessing patients with calcific aortic stenosis.
  • To discuss the evolving landscape of AS assessment beyond traditional echocardiography.

Main Methods:

  • Utilizing Doppler echocardiography for initial stenosis severity classification.
  • Investigating advanced imaging modalities for improved patient assessment.
  • Exploring the role of serum biomarkers in risk stratification.
  • Considering genetic assessment as a future diagnostic tool.

Main Results:

  • Doppler echocardiography remains the standard for classifying stenosis severity.
  • Research is ongoing to enhance patient identification and risk assessment.
  • No current medications have been successful in preventing AS.

Conclusions:

  • AS assessment is shifting from solely echocardiographic gradients to a multimodal approach.
  • Future surveillance will incorporate advanced imaging, serum biomarkers, and genetic data.
  • This transition aims for more precise patient management and risk stratification.

Keywords:
aortic stenosisaortic valvebiomarkersechocardiographyfuture prospectiveimagingvalvular disease

More Related Videos

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement08:50

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

12.3K
O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy09:24

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

Published on: October 6, 2022

4.3K

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
649
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
406
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
313
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
313
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
354
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
499