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Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

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Related Experiment Video

Updated: Feb 24, 2026

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Amelogenesis Imperfecta: Case Study.

C Leevailoj, S Lawanrattanakul, K Mahatumarat

Operative Dentistry

|August 23, 2017

Summary

Amelogenesis imperfecta (AI) is a rare genetic disorder affecting tooth enamel. Comprehensive, interdisciplinary treatment from childhood into adulthood can restore function and aesthetics for patients with AI.

Area of Science:

Dentistry
Genetics
Oral Health

Background:

Amelogenesis imperfecta (AI) encompasses rare genetic disorders of tooth development, inherited as a dominant trait.
Characterized by abnormal enamel formation due to gene mutations affecting enamel quality/quantity, AI impacts primary and permanent teeth, causing esthetic and functional issues.

Observation:

A case report details a patient diagnosed with AI in childhood, experiencing diminished confidence due to the condition.
The patient's lifelong interdisciplinary treatment involved initial restoration with resin composite veneers and stainless-steel crowns.

Findings:

Orthodontic correction for malocclusion was performed using a fixed appliance upon eruption of permanent dentition.
The long-term treatment strategy included plans for all-ceramic crowns and veneers to enhance aesthetics and function.

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Implications:

Effective management of AI requires a collaborative, interdisciplinary approach among dental specialists.
Comprehensive treatment planning is essential for achieving long-term functional and esthetic solutions for AI patients.