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Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
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Protein Clustering Shapes Polarity Protein Gradients
1Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.
Developmental Cell
|August 23, 2017
Abstract:
In this issue of Developmental Cell, Dickinson et al. (2017) and Rodriguez et al. (2017), along with Wang et al. (2017) in Nature Cell Biology, show how PAR protein oligomerization can dynamically couple protein diffusion and transport by cortical flow to control kinase activity gradients and polarity in the C. elegans zygote.
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