Related Experiment Video For Atrophic gastritis
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[Associations between Body Mass Index and Chronic Atrophic Gastritis and Intestinal Metaplasia]
Nari Kim1, Chang Ho Youn1, A Sol Kim1
1Department of Family Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Background/Aims:
Chronic atrophic gastritis (AG) and intestinal metaplasia (IM) of the stomach are premalignant lesions. The present study aimed to examine the associations between obesity and these lesions.
Methods:
A total of 2,997 patients, who underwent gastroscopy, participated in this study, excluding those who had been diagnosed with gastric cancer. Participants were divided into four groups based on their body mass index (BMI). The risk of AG and IM with increasing BMI was analyzed in men and women, separately.
Results:
The association between BMI and AG was not significant. After adjusting for age, smoking, alcohol, and AG, the odds ratios for IM in the overweight, obesity, and severe obesity groups were 2.25 (95% confidence interval [CI], 1.50-3.37), 2.32 (95% CI, 1.58-3.42), and 4.86 (95% CI, 2.04-11.5) in men, and 2.66 (95% CI, 1.29-5.47), 4.46 (95% CI, 2.28-8.75), and 9.57 (95% CI, 3.26-28.12) in women, compared with the normal BMI group.
Conclusions:
Gastric IM was significantly associated with increased BMI.
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