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Related Concept Videos

Clinical Trials01:16

Clinical Trials

10.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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Clinical Trials: Overview01:11

Clinical Trials: Overview

5.1K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
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Preclinical Development: Overview01:28

Preclinical Development: Overview

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Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
6.1K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.3K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.3K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Related Experiment Video

Updated: Feb 24, 2026

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

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Clinical trials in dermatology.

K Torre1, M Shahriari1

  • 1Department of Dermatology, University of Connecticut Health Center, Farmington, CT.

International Journal of Women'S Dermatology
|August 24, 2017
PubMed
Summary

Clinical trials are vital for medical progress, especially in dermatology for conditions like psoriasis. These studies validate new treatments, improving both disease status and patient quality of life.

Keywords:
clinical trialscontrolleddesigndouble-blindedplaceborandomized

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Area of Science:

  • Dermatology and Clinical Research

Background:

  • Randomized, double-blinded, placebo-controlled studies are essential for medical advancement.
  • Common skin conditions like psoriasis and atopic dermatitis significantly impact patients' quality of life.

Purpose of the Study:

  • To discuss the processes, resources, and challenges of clinical trials units.
  • To highlight the importance of clinical trials in validating new dermatological therapies.

Main Methods:

  • Review of clinical trial unit operations.
  • Discussion of challenges in study execution.

Main Results:

  • Clinical trials yield treatments with objective and subjective patient benefits.
  • Evidence-based medicine relies on validated clinical trial data.

Conclusions:

  • Engaging in clinical trials is critical for effective patient treatment with innovative therapies.
  • Trial-validated treatments ensure the highest standard of care in medicine and dermatology.