[Viscoelasticity-based treatment of bleeding injuries]

Area of Science:

• Trauma and Emergency Medicine
• Hematology
• Point-of-Care Diagnostics

Background:

• Uncontrolled hemorrhage is the primary preventable cause of death in trauma patients.
• Trauma-induced coagulopathy is recognized as a critical factor impacting survival.
• Current treatment involves damage control resuscitation with predefined blood product ratios.

Purpose of the Study:

• To review clinical challenges associated with viscoelastic procedures in trauma care.
• To present current expert recommendations for viscoelastic diagnostics and therapy.
• To highlight the potential of viscoelasticity-based approaches over traditional methods.

Main Methods:

• Literature review of clinical issues and expert recommendations.
• Focus on viscoelasticity-based diagnostics for whole blood analysis.
• Emphasis on point-of-care application for timely results.

Main Results:

• Viscoelasticity-based diagnostics provide qualitative assessment of thrombus formation (initiation, dynamics, sustainability).
• These methods offer therapeutically relevant information for guiding treatment.
• Ease of handling and rapid results make it suitable for point-of-care settings.

Conclusions:

• Viscoelasticity-based diagnostics and therapy represent a promising alternative to classical blood product resuscitation.
• These methods can provide crucial insights into coagulopathy at the point of care.
• Further integration of viscoelasticity-based approaches is recommended for managing severe trauma.